Software-Based Chemical Screen Could Minimize Animal Testing Anna Azvolinsky Jul 13, Researchers develop a machine-learning tool for toxicity analyses that is more consistent in predicting chemical hazards than assays on animals. Ashley Yeager Jun 21, Nearly signatories, including four Nobel Prize winners, urge openness about animal experiments.
Wildlife Alternatives to Animal Testing During a government meeting about funding for research, former U. Elias Zerhouni admitted that experimenting on animals to help humans has been a major failure. He told his colleagues: These and other non-animal methods are not hindered by species differences that make applying animal test results to humans difficult or impossible, and they usually take less time and money to complete.
Here are just a few examples of the range of state-of-the-art non-animal research methods available and their demonstrated benefits: The chips can be used instead of animals in disease research, drug testing, and toxicity testing and have been shown to replicate human physiology, diseases, and drug responses more accurately than crude animal experiments do.
A variety of cell-based tests and tissue models can be used to assess the safety of drugs, chemicals, cosmetics, and consumer products. It replaces the use of guinea pigs or mice, who would have been injected with a substance or had it applied to their shaved skin to determine an allergic response.
The non-animal methods replace the crude use of rabbits in this painful procedure. Computer in silico Modeling Researchers have developed a wide range of sophisticated computer models that simulate human biology and the progression of developing diseases.
Studies show that these models can accurately predict the ways that new drugs will react in the human body and replace the use of animals in exploratory research and many standard drug tests.
Companies and governments are increasingly using QSAR tools to avoid animal testing of chemicals, and PETA actively promotes and funds their use internationally. Volunteers are given an extremely small one-time drug dose, and sophisticated imaging techniques are used to monitor how the drug behaves in the body.
Advanced brain imaging and recording techniques—such as functional magnetic resonance imaging fMRI —with human volunteers can be used to replace archaic experiments in which rats, cats, and monkeys have their brains damaged.
These modern techniques allow the human brain to be safely studied down to the level of a single neuron as in the case of intracranial electroencephalographyand researchers can even temporarily and reversibly induce brain disorders using transcranial magnetic stimulation.
The most high-tech simulators mimic illnesses and injuries and give the appropriate biological response to medical interventions and injections of medications. Ninety-seven percent of medical schools across the U. For more advanced medical training, systems like TraumaMan —which replicates a breathing, bleeding human torso and has realistic layers of skin and tissue, ribs, and internal organs—are widely used to teach emergency surgical procedures and have been shown in numerous studies to impart lifesaving skills better than courses that require students to cut into live pigs, goats, or dogs.
Visit the PETA International Science Consortium website for more information on the global work of PETA and its affiliates to promote the development and use of modern non-animal research and testing methods.
A list of alternative toxicity-testing methods approved by regulators can be found hereand a list of organizations involved in the development of non-animal methods can be found here.Here are just a few examples of the range of state-of-the-art alternatives to animal testing available and their demonstrated benefits.
and drug responses more accurately than crude animal experiments do. Some companies, such as the HµRel Corporation. Scientists use animals to learn more about health problems that affect both humans and animals, and to assure the safety of new medical treatments.
Medical researchers need to understand health problems before they can develop ways to treat them. The latest news and comment on animal experimentation.
The Scientist's articles tagged with: animal testing. A report finds a decline in the number of experiments involving animals in , noting a particular decrease in procedures on dogs and primates.
The history of animal testing goes back to the writings of the Ancient Greeks in the 4th and 3rd centuries BCE, with Aristotle (– BCE) and Erasistratus (– BCE) one of the first documented to perform experiments on animals. Galen, a physician in 2nd-century Rome, dissected pigs and goats, and is known as the "Father of Vivisection.".
The federal government and many health charities waste precious dollars from taxpayers and well-meaning donors on animal experiments at universities and private laboratories, instead of supporting promising clinical, in vitro, epidemiological, and other non-animal studies that could actually benefit humans.